Which is better Persen or Novopassit?


Description of Glycine

Glycine is a nootropic drug, the main active substance is an amino acid. It is necessary for the development and proper functioning of the human body. The amino acid has many important functions, but the most important is maintaining the normal functioning of the nervous system.

Glycine is used for stressful situations, physical and mental stress, insomnia, neuroses, and depression.

Effect of the drug on the body:

  • relieves irritability and aggression;
  • normalizes sleep;
  • reduces the inhibitory effect on the nervous system provoked by alcoholic beverages;
  • stimulates mental activity;

  • restores cerebral blood supply.

The medication is produced in the form of lozenges. The dosage is 4-6 pcs. per day for a month. This component, natural to the body, almost never causes negative effects or overdose. The drug is allowed for infants, adults and elderly patients. Can be used during pregnancy and breastfeeding. It is indicated with extreme caution in patients with arterial hypotension, since taking Glycine often increases blood pressure.

For diseases of the cardiovascular system, accompanied by increased blood pressure, it is important to choose an antihypertensive drug that has few side effects. Read more in the article: “lozap and lisinopril: analogues and replacement.”

Characteristics of Afobazole

Afobazole is a tranquilizer that exhibits a calming effect without suppressing the central nervous system. The main active ingredient is fabomotizole, which is a selective anxiolytic. The drug is effective for various psycho-emotional disorders and depression.

Afobazole is recommended for people with somatic, dermatological pathologies, and oncology.

Indications for use:

  • cardiopsychoneurosis;
  • anxiety, neurasthenia;
  • sleep disturbance;

  • mood change, adaptation.

Afobazole contraindications and negative effects:

  • period of breastfeeding, pregnancy;
  • individual intolerance to constituent substances;
  • patients under 18 years of age.

Adverse effects are extremely rare. In case of overdose, drowsiness, general malaise, and weakness appear. Activated carbon or gastric lavage will help eliminate this condition.

Dosage of the drug: a single dose is 10 mg, the therapeutic course is 3-4 weeks three times a day after meals. To restore sleep, up to 60 mg is prescribed. Afobazole helps eliminate alcohol syndrome and improves well-being when quitting smoking.

Capoten and Captopril are drugs for the symptomatic treatment of hypertension. They do not eliminate the causes of the disease, but only reduce blood pressure and maintain its normal levels, provided they are taken systematically. Read more in the article: “what is the difference between capoten and captopril.”

Efficiency

As we already said in the previous article about comparing drugs, it is difficult to predict the effect of a particular drug. However, several assumptions can be made. Two of the three components of Persen are also present in the competitor, however, in addition to this, it has five more active ingredients. Therefore, in terms of efficiency, we still give the palm to Novopassit. It is also worth saying that the effectiveness of Persen can be partially verified in the following way. Try brewing valerian herb or taking a few tablets of regular pharmacy valerian. If there is no effect at all, then, most likely, the effect of Persen will also be low. The combination of all of the above properties will ultimately affect adherence to therapy, because the dosage regimen is similar (1-2 tablets three times a day).

We can discuss for a long time various aspects of competitors: the ability of Novopassit to reduce the effectiveness of hormonal contraception, the ability to drive a vehicle while using Persen and the restriction on that of another drug, the likelihood of developing constipation when taking Persen Forte. However, the conclusion of the article, to the probable regret of readers, will be different. Before using these sedatives, it is difficult to predict which one is best for a particular person. No full-fledged studies aimed at identifying the degree of effectiveness of drugs or assessing them according to other criteria have been carried out. When choosing, you can focus on the above pros and cons, and make decisions based on what is more important for you specifically.

Features of Novopassit

Novopassit is a sedative medicine of plant origin. Main ingredients: lemon balm, St. John's wort, hops, valerian, hawthorn. Additional components: glycerol, cellulose, magnesium stearate. Effective for:

  • feeling irritable;
  • chronic fatigue;
  • memory loss;
  • sleep disturbance.

The drug exhibits a slight sedative effect and has an antispasmodic effect when feeling pain or spasms.

Novopassit is produced in syrup, tablet form, and liquid extract. Directions for use: 1-2 tablets. three times a day, solution - 5-7 drops. 3 times. Since Novopassit is based on plant elements, it has almost no contraindications or adverse effects. It is allowed for pregnant and lactating women, as well as patients over 12 years of age. The only side effects are allergies to substances, rarely - nausea, heartburn, indigestion. Not used for epilepsy, bradycardia. It is forbidden to combine Novopassit with alcohol.

Characteristics of Persen

The drug is available in the form of tablets, which contain herbal extracts such as:

  • valerian;
  • Melissa;
  • mint.

The medication relieves spasms and eliminates symptoms of anxiety, providing a mild calming effect. The medicine is used for sleep disorders, constant stress and emotional overload. The drug can be used during PMS to eliminate increased irritability, mood swings and aggression.

It is recommended to take the medication for no more than 6 weeks. There is no withdrawal syndrome, since the medicine contains only natural ingredients. Children over 12 years of age are allowed to receive therapy. Negative reactions occur rarely and manifest themselves in the form of itching, rashes and constipation.

The drug should not be taken if you have low blood pressure, constant lethargy or gallbladder disease. The medication can be used for therapy only after consultation with a gastroenterologist if there are pathologies associated with increased production of gastric juice.

The medicine affects the speed of reactions, so work that requires increased concentration should be approached with caution. If heartburn, stomach pain and nausea occur during therapy, it is recommended to discontinue the drug and replace it with another one.

It is not recommended to combine the medication with drugs that affect the central nervous system: antidepressants and anti-anxiety drugs.

Persen affects the speed of reactions, so work that requires increased concentration should be approached with caution.

Afobazole or Glycine - which is better?

Which remedy to use depends on the severity of the symptoms. For severe anxiety, it is better to use Afobazole. In case of simple nervous overexcitation or irritability, preference can be given to Glycine. It is also effective at the time of intellectual stress; Afobazole does not increase cognitive abilities.

Glycine is allowed for children and women during pregnancy; Afobazole is contraindicated in these groups.

Similarities of drugs:

  1. medications affect the nervous system and exhibit a sedative effect, but Afobazole has a more intense anti-anxiety effect;

  2. occasionally lead to negative phenomena;
  3. both medications reduce symptoms of depressive disorder and help cope with insomnia;
  4. the products do not increase the effects of alcoholic beverages.

These drugs can be used in combination; their compatibility does not cause adverse events. If treatment is carried out with two means, then the interval between them is at least 30 minutes.

Novopassit or Glycine - what to choose?

When purchasing a product, you must rely on the effect expected from use. When the body lacks an amino acid, Glycine can fill it. Mainly used by students and preschoolers to increase mental and physical activity. Also indicated for elderly patients to restore sleep and improve memory. The drug is combined with Mexidol, Vinpocetine.

Similarities and differences:

  1. They have the same effect on the body.
  2. Both drugs are safe because they contain natural substances.
  3. Novopassit is a sedative, Glycine is a nootropic agent. The first is a herbal medicine, the second is an amino acid.

For family troubles, nervousness at work and other life situations, doctors prescribe Novopassit. The product is not addictive compared to antidepressants, tranquilizers, and has natural ingredients that will help you achieve the desired result. Novopassit relieves anxiety, stress, and insomnia.

Novopassit or Persen - which is better?

Medicines based on herbal products are usually well tolerated and therefore have a large following.

Clinical trial results indicate that the combination of valerian and lemon balm improves sleep disturbances to the same extent as benzodiazepines, but without significant sedation.

Valerian as a single drug or in combination with other drugs can be prescribed not only to adults, but also to children.

In our pharmacies you can buy Novopassit and Persen, which contain this wonderful plant. Let's look at Novopassit or Persen - which helps better if you experience irritability, anxiety or suffer from insomnia.

There are contraindications, consult a specialist

What is the difference between Persen and Novopassit?

Novopassit and Persen are sedatives that are sold without a prescription. Novopassit is available in the form of a solution in a bottle or packaged in small 10 ml bags. It is also available in tablet form.

Persen is a tablet. In addition, the line of this brand contains the drug Persen Night, which has a stronger effect due to the increased dosage of active ingredients. Produced in capsule form.

If Persen and Novopassit are compared in terms of the composition of the components, a more significant difference will be revealed.

Persen or Novopassit - which is better in terms of richness of the composition?

Novopassit contains an extract of vegetative organs (leaves, rhizomes, roots, flowers) of the following plants:

  1. Valeriana officinalis - valerian,
  2. Hypéricum perforatum - St. John's wort,
  3. Melissa officinalis - lemon balm,
  4. Passiflora incarnata - passion flower,
  5. Sambúcus nígra - elderberry,
  6. Húmulus lúpulus - hops,
  7. Crataegus monogyna - hawthorn.

In addition, the medicine contains guaifenesin, a chemical derivative of propylene glycol and a substance that is extracted from the resin of the guaiac tree.

In quantitative terms, the components in Novopassit are distributed as follows:

  • per tablet 0.2 g of guaifenesin and 0.157 g of plant dry extract,
  • in 1 ml of solution 0.04 g of guaifenesin and 0.077 g of plant liquid extract

Line of drugs "Novo-Passit"

Difference in composition between tablets and Novopassit solution Component Novopassit (1 tablet) Novopassit solution (5 ml) Mixture of medicinal plant extracts (mg): Guaifenesin (mg):

157,5387,5
200200

The difference between Persen and Novopassit is a more modest composition of active ingredients. It contains only three ingredients:

  1. valerian,
  2. mint
  3. and Melissa.

Persen tablets 60 pcs. (new packaging)

There are also differences between representatives of the Persen brand. Persen Night contains 75 mg more.

The difference in composition between “Persen” and “Persen Night” Component Persen Persen Night Valerian (mg) Melissa (mg) Mint (mg)

50125
2525
2525

Capsules P. Night

Characteristics of plant components in Novopassit and Persen

It can be said that all the herbal components present in the Novopassit or Persen preparations have undergone the longest and most large-scale clinical trials, having been used in folk medicine in many countries for many centuries.

Nowadays, randomized clinical trials have confirmed the beneficial effects of valerian extracts on insomnia.

75 trial participants who received 0.6 g of valerian extract for 28 days experienced improved sleep quality.

It was the same as in patients taking oxazepam, but with valerian there were no side effects characteristic of benzodiazepines.

The collection of herbs from which Novopassit is prepared has not only soothing properties due to the presence of valerian, passionflower, hops and lemon balm, but also general strengthening properties.

St. John's wort is otherwise called a “remedy for 99 diseases”; elderberry is a medicinal plant with anti-inflammatory, bactericidal, astringent, diaphoretic and diuretic effects.

Hawthorn is considered a “heart” medicine because it improves the supply of oxygen to the heart muscle, increases its energy balance, and reduces capillary fragility and permeability.

Guaifenesin has been used as an expectorant since the 50s of the last century. Now, for example, it is included in the drug Ascoril. However, its pronounced anxiolytic and muscle relaxant effect allows it to be used as a part of sedatives. In addition, guaifenesin can enhance the effect of hypnotics included in the drug.

Which is cheaper: Novopassit or Persen?

Let's look at the difference between Novopassit and Persen in terms of price. Both drugs are imported: Persen is produced by Lek (Slovenia), and Novopassit is produced by IVAX Pharmaceuticals (Czech Republic). 30 Novopassit tablets cost an average of 500 rubles, and 200 ml of solution costs about 320 rubles. Persen tablets (40 pieces) are 30% cheaper than Novopassit tablets. But Persen night is 25% more expensive than Novopassit.

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Source: https://www.kliwi.ru/2016/04/novopassit-ili-persen-chto-luchshe.html

Afobazole or Novopassit - which is better?

Sedatives improve the functioning of the central nervous system. Both medications relieve symptoms, but affect the body differently.

Similarities and differences between them:

  1. They have the same indications and contraindications (pregnancy, lactation).
  2. The main difference is the chemical composition. Novopassit is created from plant substances, Afobazol is a synthetic medicine.
  3. The price of Novopassit is 300-750 rubles, Afobazol - 350-400 rubles.

When choosing a product, it is necessary to take into account the age and well-being of the person. Depending on the physical activity or type of activity, one drug may be better or worse than another. Novopassit or Afobazol is better; according to doctors, the first has a more delicate effect on the central nervous system, is well tolerated by people and rarely provokes negative reactions. However, for long-term treatment it is better to use Afobazole, but only under the supervision of a specialist.

Analogues of sedatives

If for some reason the patient cannot take the above medications, they can be easily replaced with others with a similar action and effect.

Table with similar drugs:

A drugActive substanceManufacturerPrice
GrandaxintofisopamHungaryfrom 369 rub.
Phenibutaminophenylbutyric acidRussia, Latvia, Belarusfrom 149 rub.
AdaptolmebicarLatviafrom 1138 rub.
PhenazepambromodihydrochlorophenylbenzodiazepineRussia Valenta FARM JSCfrom 150 rub.
Tenotenantibodies to brain-specific protein S-100Russia Moscowfrom 267 rub.
Picamilonnicotinoyl gamma-aminobutyric acidRussiafrom 146 rub.
PiracetampiracetamIndiafrom 62 rub.
Cortexinbovine cerebral cortex polypeptidesGeropharm LLCfrom 1321 rub.
CerebrolysinCerebrolysin concentrateAustriafrom 1529 rub.
Ataraxhydroxyzine hydrochlorideBelgiumfrom 286 rub.

The drugs will help relieve feelings of fear, tension and anxiety.

Persen is an effective drug

Persen is a sedative of plant nature; several main components predominate in its composition: lemon balm, mint, valerian. The medicinal properties and pharmacological effects of the drug are due to its natural components. The drug has an antispasmodic, calming effect and has a slight effect on the nervous system. Persen is effective for:

  • increased nervous excitability;
  • sleep disturbance;
  • irritability, depression.

You should not take the medicine if you have:

  • intolerance to lactose, fructose;
  • children under 12 years of age;
  • lactation, pregnancy;
  • susceptibility to constituent substances;
  • tendency to increase blood pressure;
  • gallstone pathology;
  • lack of lactase in the body.

Mint, which is part of the medication, has a vasoconstrictive effect on the blood vessels of the brain. The drug is often used for VSD and insomnia. Since Persen contains natural substances, it is not addictive.

Grandaxin is an effective tranquilizer

Grandaxin has an anxiolytic effect and almost no anticonvulsant or sedative effect. The medicine is considered a psycho-vegetative regulator and helps get rid of autonomic disorders. Shows moderate stimulating ability. Due to the lack of muscle relaxant results, the drug can be used in patients with myasthenia gravis and myopathy.

Grandaxin is a “daytime” medication, that is, it does not cause drowsiness, addiction or withdrawal symptoms.

Negative phenomena:

  • headache, severe irritability, confusion;
  • skin rash;

  • muscle pain;
  • loss of appetite, abnormal stool, dry mouth.

The tablets should be used with caution for epilepsy, atherosclerosis, and closed-angle glaucoma. Not prescribed during lactation, 1st trimester of pregnancy. Directions for use: 1-2 tablets. three times a day for 3 weeks. The maximum daily dose is 300 mg.

Phenibut is an anti-anxiety drug

Phenibut is a nootropic medicine that has psychostimulating, antioxidant, and tranquilizing effects. Improves brain function by restoring tissue metabolism and improving cerebral circulation. The drug reduces or completely eliminates feelings of anxiety, tension, and improves sleep.

Phenibut enhances the effect of narcotic analgesics, hypnotics and antipsychotic drugs. Indications for use:

  • nightmares in elderly patients;
  • psychopathy;
  • asthenic, neurotic conditions;
  • stuttering in children;

  • obsessive-compulsive neurosis;
  • additional remedy in the treatment of alcoholism.

The dose of Phenibut and duration are determined by individual characteristics, the age of the patient, and tolerability of the medication. A single dose of medication ranges from 20-750 mg - for adults; from 20-250 mg - for a child. It is indicated with special caution for liver failure and digestive diseases.

Adaptol is an analogue of Afobazole

The active component of Adaptol is tetramethyltetraazabicyclooctanedione, the release form is tablets. Relieves anxiety, worry, fear, internal psycho-emotional stress. The calming result is not associated with muscle relaxation or changes in motor coordination. It does not reduce motor or mental ability, therefore it is recommended for pupils, students and working people. Does not cause a feeling of euphoria.

It does not have a hypnotic effect, but it increases the effect of sleeping pills and improves sleep. Adaptol improves or eliminates nicotine withdrawal. In addition to the sedative, it produces nootropic assistance. Normalizes cognitive functions, attentiveness, does not stimulate signs of psychopathological disorders, namely delirium, excessive excitability.

Adaptol dosage: 500 mg three times a day, taken regardless of meals. The maximum dose is 10 g per day. The duration of therapy is up to 2 months.

Tenoten is an anxiolytic drug

Tenoten is a nootropic drug that provides anti-anxiety results without causing adverse muscle relaxant, hypnotic effects. Normalizes the tolerance of emotional stress. Shows antihypoxic, antidepressant, antiamnestic effects.

In case of hypoxia or intoxication, Tenoten produces a neuroprotective effect, limiting the area of ​​damage and improving memory. The drug should not be used by patients under 18 years of age or with high susceptibility to the constituent substances.

Directions for use: tablets should be taken before meals, 1-2 tablets. twice a day. If absolutely necessary, the frequency is increased up to 4 times. Since activating elements predominate in the drug, the last dose should be taken at least 2 hours before going to bed.

The therapeutic course is 1-3 months. If there is no improvement in the condition within 4 weeks, the patient should consult a doctor.

Comparison of drugs

A brief overview of the main characteristics of these drugs will help you compare and find out which works more effectively - Persen or Novo-Passit. For analysis, such points of the instructions for use as composition and mechanism of action, indications, as well as contraindications and side effects are important.

Compound

The active ingredients of Persen are extracts of medicinal herbs. Their dosage depends on the dosage form (tablets or Persen night capsules):

  • valerian – 50 and 125 mg (for tablets and capsules, respectively);
  • lemon balm - 25 and 25 mg;
  • peppermint – also 25 mg.

Novo-passit contains many more components, their composition and quantity also depends on the dosage form. The tablets contain:

  • powders of valerian rhizomes (25 mg) and cyanosis (10 mg);
  • lemon balm and motherwort extracts (10 mg each);
  • vitamin C (ascorbic acid) – 8 mg.

The liquid dosage form contains the following active substances per 100 ml:

  • extracts of valerian, lemon balm, St. John's wort, hawthorn, passionflower, hops and elderberry – 7.75 g;
  • Guaifenesin – 4 g.

Mechanism of action

  • The combination of valerian, mint and lemon balm in Persen tablets has a variety of effects on the body. Valerian root is a long-known sedative that reduces nervous excitability. Melissa and mint also calm the nervous system, make it easier to fall asleep if you have insomnia, and also relieve spasms of the smooth muscles of blood vessels.
  • Extracts of medicinal herbs in tablets and solution Novo-Passit also inhibit the excitability of the nervous system, normalize the functioning of blood vessels and the heart, as well as the intestines, and eliminate sleep problems. Guaifenesin, which is part of the liquid dosage form, belongs to the group of anxiolytics - anti-anxiety drugs.

Indications

For Persen:

  • irritability;
  • sleep disorders;
  • increased nervous excitability;
  • feeling of internal tension.

For Novo-passit:

  • neurotic conditions, characterized by anxiety, fatigue, restlessness and irritability;
  • sleep disorders;
  • migraine (a disease accompanied by very intense headaches);
  • itchy dermatoses (skin diseases) caused by mental stress;
  • headaches arising from stress on the nervous system;
  • digestive disorders developing for the same reason - dyspepsia, “irritable bowel syndrome”;
  • climacteric syndrome - symptoms of hormonal changes in women during menopause;
  • constant nervous tension - “manager syndrome”.

Contraindications

For Persen:

  • intolerance to components;
  • intolerance to fructose, lactose and some other sugars;
  • age less than 12 years;
  • pregnancy, breastfeeding;
  • low blood pressure (hypotension);
  • diseases of the biliary tract.

For Novo-passit:

  • hypersensitivity to components;
  • sugar intolerance;
  • age up to 12 years;
  • breast-feeding;
  • muscle weakness (myasthenia gravis).

Side effects

Persen can cause:

  • allergies;
  • constipation;
  • spasm of the airways (bronchospasm).

A side effect of taking Novo-passit if you are intolerant to it is allergic reactions.

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